By I Barry Holland, Susan P. C. Cole, Karl Kuchler, Christopher F. Higgins
ABC Proteins is an in-depth, updated research of all that's identified in regards to the topic to this point. It discusses and compares evolution, biology and mechanism of motion of all recognized ABC proteins, together with the 1st structural stories in addition to medical implications. it will likely be invaluable to an individual attempting to remain abreast of the newest findings. This e-book is bound to turn into a vintage and should usually be up to date. Key good points* Phylogeny and Evoloution of ABC Transporters* basic points of the Mechanism of motion of ABC Transporters* Prokaryote ABC Transporters* Non-Mammalian Transporters* Multidrug Transporters* ABC Transporters, Physiological Roles and Human sickness* complete colour all through
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Extra info for ABC Proteins: From Bacteria to Man
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Membr. Biol. 176, 187–206. M. H. (1997) The photoreceptor rim protein is an ABC transporter encoded by the gene for recessive Stargardt’s disease (ABCR). FEBS Lett. 409, 247–252. , et al. (1998) Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain. J. Biol. Chem. 273, 32167–32175. , Wolfger, H. and Kuchler, K. (1999) Inventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance. Biochim. Biophys. Acta 1461, 217–236.
Chem. 275, 15526–15534. , Ito, K. and Kashiwagi, K. (2001) Polyamine uptake systems in Escherichia coli. Res. Microbiol. 152, 271–278. , Matsuzawa, Y. and Kurachi, Y. 2) a smooth muscle type ATP-sensitive Kϩ channel. J. Biol. Chem. 271, 24321–24324. PHYLOGENETIC AND FUNCTIONAL CLASSIFICATION OF ABC SYSTEMS Jekabsons, W. and Schuster, W. (1995) orf250 encodes a second subunit of an ABC-type heme transporter in Oenothera mitochondria. Mol. Gen. Genet. 246, 166–173. M. R. (1987) Cobalamin (vitamin B12) biosynthetic genes of Salmonella typhimurium.