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By Julien Bogousslavsky

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Cerebrovasc Dis 2003;16(suppl 1):20–26 36 Mehta SR, Yusuf S, Peters RJG, Bertrand ME, Lewis BS, Natarajan MK, Malmberg K, Rupprecht HJ, Zhao F, Chrolavicius S, Copland I, Fox KAA, for the Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial (CURE) Investigators: Effects of pretreatment with clopidogrel and aspirin followed by longterm therapy in patients undergoing percutaneous coronary intervention: The PCI-CURE study. Lancet 2001;358:527–533. 37 Anonymous: Major ongoing stroke trials.

Eur Heart J 1998;19:1538–1546. 26 31 Moshfegh K, Redondo M, Julmy F, Wuillemin WA, Gebauer MU, Haeberli A, Meyer BJ: Antiplatelet effects of clopidogrel compared with aspirin after myocardial infarction: Enhanced inhibitory effects of combination therapy. J Am Coll Cardiol 2000;36:699–705. 32 Leon MB, Baim DS, Popma JJ, Gordon PC, Cutlip DE, Ho KK, Giambartolemei A, Diver DJ, Lasorda DM, Williams DO, Pocock SJ, Kuntz RE: A clinical trial comparing three antithrombotic-drug regimens after coronaryartery stenting.

27 Schafer AI: Antiplatelet therapy. Am J Med 1996;101:199–209. 28 Harker LA, Marzec UM, Kelly AB, Chronos NRF, Sundell IB, Hanson SR, Herbert JM: Clopidogrel inhibition of stent, graft, and vascular thrombogenesis with antithrombotic enhancement by aspirin in nonhuman primates. Circulation 1998;22:2461–2469. 29 Herbert JM, Dol F, Bernat A, Falotico R, Lalé A, Savi P: The antiaggregating and antithrombotic activity of clopidogrel is potentiated by aspirin in several experimental models in the rabbit.

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