Download Ageing : the paradox of life by Robin Holliday PDF

By Robin Holliday

For hundreds of years humans were questioned through the inevitability of human getting older. for many of the second one half the 20 th century getting older remained a secret, or an unsolved organic challenge. on the finish of the 20 th century a striking medical discovery emerged. It was once no longer a unmarried discovery within the ordinary experience, since it used to be according to a chain of significant interconnected insights over really a protracted time period. those insights made it attainable for the first actual time to appreciate the organic purposes for getting older in animals and guy. it might already be acknowledged, besides the fact that, that the numerous observations and insights that designate getting older aren't authorised as confirmed wisdom for a very long time. the sphere continues to be choked with scientists, and non-scientists, who're simply satisfied to move on speculating concerning the 'mystery' of getting older. the purpose of this publication is to dispel lack of information through explaining in non-technical language what are the explanations for getting older and the parable of over the top prolongation of existence.

Show description

Read or Download Ageing : the paradox of life PDF

Similar basic science books

Sperm biology : an evolutionary perspective

This publication represents the 1st research of the evolutionary value of sperm phenotypes and derived sperm qualities and the prospective choice pressures accountable for sperm-egg coevolution. An knowing of sperm evolution is speedy constructing and can provide to make clear many themes from simple reproductive biology to the evolutionary procedure itself in addition to the sperm proteome, the sperm genome and the quantitative genetics of sperm.

Computed Tomography for Radiographers

The aim of this publication is to provide the reader a uncomplicated Computed Tomography for Radiographers is split into creation to computed tomography. it's also directed sections. half 1 is devoted to the technical elements of in the direction of qualifying radiographers and to all certified in keeping with­ computed tomography and half 2 to the medical points.

Immunity: the evolution of an idea

" Senior pupil Alfred Tauber argues during this daring account that universal methods to the examine of immunology are inherently fallacious in its strict dichotomy of the self and non-self, or exterior invaders. the connection among what's self and what's non-self is in fact a posh, dymanic, relational one.

Extra resources for Ageing : the paradox of life

Example text

Their continued survival would place an unwanted burden on the organism, including in some cases the development of cancer. Fat storage can be regarded as another important maintenance mechanism. In natural environments, the supply of food fluctuates. When it is abundant, some is stored in the form of fat. This is then used up in times of scarcity. Clearly this adaptation benefits survival in harsh or stressful environments. Unfortunately it has bad consequences in any environment where food is always plentiful.

We can pinpoint a fundamental principle in saying that there is a trade-off between investment in reproduction and investment in maintenance. So we find animals which grow and reproduce very quickly but have short lifespans, and animals which grow and reproduce slowly with long lifespans. But we never see the other theoretical possibilities, namely, animals which grow and breed quickly with long lifespans; and animals which grow and breed slowly with short lifespans. The former is a physiological impossibility, and the latter would lead to rapid extinction.

Chapter 4. Multiple Causes In Chapter 2, I described and listed a number of non-renewable structures in the body. Many of these can last a lifetime, but not indefinitely. What we see during ageing are progressive changes in these structures. Here I relate these changes to the multiple causes of ageing. The changes occur with a degree of synchrony, but sometimes one is in advance of the others, and then it is liable to be labelled a disease. Heart disease and Alzheimer’s disease are good examples of this.

Download PDF sample

Rated 4.43 of 5 – based on 36 votes