Download Amyloid and amyloidosis by Gilles Grateau, Robert A. Kyle, Martha Skinner PDF

By Gilles Grateau, Robert A. Kyle, Martha Skinner

This authoritative quantity includes 179 chapters by way of overseas specialists on contemporary advancements in our knowing of amyloid proteins, protein folding issues, and new and proposed scientific trials in amyloidosis. subject matters contain detection and characterization suggestions; organic services; genetics; issues, analysis, and coverings, together with organ transplants and drug treatments; effects from broad medical reviews; and epidemiology. it is a necessary source for clinicians who deal with sufferers with systemic and localized varieties of amyloidosis, and for researchers in biochemistry, neurobiology, and cellphone biology.

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Lachmann, H. , Gallimore, J. , Lovat, L. , Norcross, R. , Kemp, J. , Taylor, G. , Wood, S. P. & Hawkins, P. N. (2002). Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis. Nature 417, 254-9. 3. Lachmann, H. J. & Hawkins, P. N. (2003). Novel pharmacological strategies in amyloidosis. Nephron Clin Pract 94, c85-8. si In several cases of single point mutations inverse correlation between stability and propensity to form amyloidlike fibrils has been demonstrated (1).

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